stopping multiple buttons from playing

Hello. I have a kind of complicated question. It has to do with sounds on buttons. I have run a site that administers quizzes to children. Some of these children are very young and cannot read so we have to have icons that they can click on and the instructions are voiced to them. My questions has 2 parts:

1. IS there a way to only play a sound once when a button is clicked? These are very young kids who will continue to click on the icons therefore causing the voice to repeat, and repeat.

2. The second question has to do with allowing multiple buttons to "disable" themselves until the one that is playing finishes? There's multiple buttions on a page which can be distracting to yound children who want to click on all of them.

- I have 168 buttons to edit, so the easier the suggestion the better.

Thanks!