If statement

if for example i have a global variable called M that is an integer and i assign a value to it here and there and there comes a situation that i want to examine the value of M how can i do it?
i mean if for exmaple i want to say if M is not equal to 6 how can i say it in VB?

in C you can simply say if(M !=6)
in VB i tried something like if NOT(M=6) then ....
but it didnt work
how do i do it?

If M <> 6 Then